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[Acute fibrinous and organizing pneumonia]

Cláudia Santos1, Fátima Fradinho2, Alexandra Catarino2

  • 1Interna Complementar de Pneumologia.

Revista Portuguesa De Pneumologia
|April 15, 2020
PubMed

Insights

Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct interstitial lung disease. This review and case study highlight its unique features compared to other acute lung injuries.

Area of Science:

  • Pulmonary Pathology
  • Histopathology
  • Interstitial Lung Diseases

Context:

  • Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct histologic pattern.
  • It presents with intra-alveolar fibrin and diffuse organizing pneumonia.
  • AFOP requires differentiation from other acute lung injury patterns like DAD, OP, and EP.

Purpose:

  • To review the literature on AFOP.
  • To describe a clinical case with unusual imaging and outcome.
  • To enhance understanding of this interstitial pulmonary disease.

Summary:

  • AFOP is characterized by fibrin "balls" and diffuse organizing pneumonia.
  • Symptoms can be acute or subacute.
  • This condition is histologically distinct from Diffuse Alveolar Damage (DAD), Organizing Pneumonia (OP), and Eosinophilic Pneumonia (EP).

Impact:

  • Improves diagnostic criteria for AFOP.
  • Highlights the importance of distinguishing AFOP from other acute lung conditions.
  • Provides insights into the clinical presentation and management of AFOP.
Keywords:
AFOPfibrin ballsorganizing pneumonia

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