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Published on: August 1, 2019
Improving fecal occult blood testing compliance using a mailed educational reminder
Jeffrey K Lee1, Veronica Reis, Shanglei Liu
1Department of Medicine, VA San Diego Healthcare System and University of California, San Diego, CA 92161, USA.
Journal of General Internal Medicine
|September 24, 2009
Summary
A mailed educational reminder significantly boosted fecal occult blood testing (FOBT) card return rates for colorectal cancer (CRC) screening. This simple intervention improved compliance, highlighting its potential to reduce CRC mortality.
Area of Science:
- Oncology
- Preventive Medicine
- Public Health
Background:
- Colorectal cancer (CRC) remains a leading cause of cancer-related mortality in the U.S.
- Screening via fecal occult blood testing (FOBT) is proven to reduce CRC incidence and mortality.
- Low patient compliance with FOBT presents a significant barrier to effective screening.
Purpose of the Study:
- To evaluate the effectiveness of a mailed educational reminder in increasing FOBT card return rates.
- To identify predictors of patient compliance with FOBT screening.
Main Methods:
- A blinded, randomized controlled trial was conducted at the VA Medical Center, San Diego.
- 775 patients aged 50+ referred for FOBT were randomized into usual care or intervention groups.
- The intervention group received a mailed reminder 10 days after FOBT card distribution.
Main Results:
- The intervention group showed a significantly higher return rate (64.6%) compared to the control group (48.4%) (P < 0.001).
- Receiving a mailed reminder and prior FOBT return history were predictors of compliance.
- Current or recent illicit drug use was associated with lower FOBT return rates.
Conclusions:
- A simple mailed educational reminder is an effective strategy to improve FOBT compliance for CRC screening.
- Targeted interventions can enhance participation in CRC screening programs.
- Further research into barriers to screening in specific populations may be warranted.

