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Updated: Jun 20, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Abdominal aspergillosis: CT findings.

Suk Keu Yeom¹, Hye Jin Kim, Jae Ho Byun

¹Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-dong, Songpa-gu, Seoul 138-736, Republic of Korea. pagoda20@hanmail.net

European Journal of Radiology

|September 25, 2009

Summary

Computed tomography (CT) findings in immunocompromised patients with abdominal aspergillosis often show angioinvasive features or abscesses. Familiarity with these CT findings can aid in diagnosing this rare and fatal condition.

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Last Updated: Jun 20, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Area of Science:

Radiology
Medical Imaging
Infectious Diseases

Background:

Abdominal aspergillosis is a rare but fatal invasive fungal infection.
Immunocompromised patients, particularly those with hematologic malignancies or solid organ transplants, are at high risk.

Observation:

This study retrospectively evaluated CT findings in six immunocompromised patients with pathologically confirmed abdominal aspergillosis.
CT scans were analyzed for lesion characteristics, including location, number, morphology, attenuation, and contrast enhancement.

Findings:

Aspergillosis involved various abdominal organs, including blood vessels, liver, spleen, gastrointestinal tract, kidneys, peritoneum, and retroperitoneum.
CT demonstrated angioinvasive features such as vascular thrombosis and pseudoaneurysm leading to organ infarction or perforation.
Other findings included low-attenuating lesions resembling abscesses, bowel wall thickening mimicking typhlitis, and peritoneal/retroperitoneal infiltration.

Implications:

Recognizing characteristic CT findings of abdominal aspergillosis is crucial for early diagnosis.
Familiarity with these imaging features can improve diagnostic accuracy for this life-threatening infection.