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Updated: Feb 19, 2026

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
Published on: September 8, 2023
When the diagnosis is a zebra: pulmonary artery aneurysm
Vishnu Singh1, Mariya Vaksman, Igor Mamkin
1Division of Cardiology, New York Methodist Hospital-Weill Medical College of Cornell University, Brooklyn, New York 11215, USA.
Abstract:
Some ailments maypresent so distinctively that the diagnosis is often unquestionable. Other cases, however, may present typically, but have atypical findings. We describe a case of a patient who presented to our institution with recurrent hemoptysis. The clinical features were suggestive of an underlying infection or malignancy. When these were ruled out, the search for a zebra had begun. The patient underwent sixty four-slice computerizedtomographic angiography (CTA) which revealed a right pulmonary artery aneurysm (PAA). Timely involvement of interventional radiologists and thoracic surgeons prevented a potentiallylife-threatenninghemorrhage. This case underlines the importance of awareness of this condition in the formulation of a differential diagnosis forhemoptysis. PAAis a rare condition that is either congenital or acquired. Common acquired etiologies include chronic thromboembolic pulmonary hypertension, infections (syphilis and tuberculosis), vasculitis (Behcet's and Hughes-Stovin syndromes), neoplasms (primaryandmetastatic), andtrauma(most often iatrogenic).
Insights
A rare pulmonary artery aneurysm (PAA) caused recurrent hemoptysis in a patient. Prompt diagnosis via CT angiography and intervention averted a life-threatening hemorrhage, highlighting PAA in differential diagnoses.
Area of Science:
- Cardiology
- Radiology
- Thoracic Surgery
Background:
- Recurrent hemoptysis can stem from various causes, including infection or malignancy.
- Atypical presentations of common conditions necessitate a broad differential diagnosis.
Observation:
- A patient presented with recurrent hemoptysis, initially suspected to be infection or malignancy.
- Standard investigations for infection and malignancy were negative.
- Sixty-four-slice computed tomographic angiography (CTA) revealed a right pulmonary artery aneurysm (PAA).
Findings:
- Pulmonary artery aneurysm (PAA) is a rare condition, congenital or acquired.
- Acquired PAA etiologies include chronic thromboembolic pulmonary hypertension, infections, vasculitis, neoplasms, and trauma.
- Timely diagnosis and intervention by interventional radiologists and thoracic surgeons prevented hemorrhage.
Implications:
- This case underscores the importance of considering pulmonary artery aneurysms in the differential diagnosis of hemoptysis.
- Increased awareness of PAA can lead to earlier diagnosis and management.
- Multidisciplinary collaboration is crucial for managing rare vascular conditions.
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