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Updated: Jun 20, 2026

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
Published on: September 8, 2023
Patterns of diacetylene-containing peptide amphiphiles using polarization holography
Maaike van den Heuvel1, An M Prenen, Jeroen C Gielen
1Department of Bio-organic chemistry, Radboud University Nijmegen, Nijmegen, The Netherlands.
Abstract:
The polarization dependence of a diacetylene polymerization was studied. For this purpose, peptide amphiphile fibers with a diacetylene moiety, which could only polymerize in the direction of the fiber, were employed. If nonaligned samples were illuminated with polarized light, only the fibers parallel to the polarization direction of the light were polymerized. With magnetically aligned fibers, spatially selective polymerization was accomplished using polarization holography.

