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Related Experiment Video

Updated: Jun 20, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

Costs and outcomes associated with IVF using recombinant FSH.

W Ledger¹, C Wiebinga, P Anderson

¹Centre for Reproductive Medicine and Fertility, Royal Hallamshire Hospital, Sheffield, UK.

Reproductive Biomedicine Online

|September 26, 2009

Summary

This study found that assisted conception units (ACUs) can achieve UK average live birth rates for in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) with lower recombinant FSH (rFSH) doses and costs. This suggests potential for more IVF/ICSI cycles within existing budgets.

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Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model

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Last Updated: Jun 20, 2026

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Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model

Published on: August 11, 2023

Area of Science:

Reproductive Medicine
Health Economics
Assisted Reproductive Technology

Background:

Clinical trial data for assisted reproduction may not reflect real-world practice.
Economic evaluations are crucial for informing healthcare service provision and budget allocation.
Understanding the costs and outcomes of IVF/ICSI in routine practice is essential.

Purpose of the Study:

To conduct an economic evaluation of IVF/ICSI cycles in a UK assisted conception unit (ACU).
To compare the costs and outcomes of routine IVF/ICSI practice with existing UK guidelines.
To assess the potential for optimizing resource allocation in assisted reproduction.

Main Methods:

Analysis of 1418 IVF/ICSI cycles from a single English ACU (October 2001-January 2006).
Evaluation of live birth rates, recombinant FSH (rFSH) dosage, and associated costs per cycle.
Comparison of study data with economic data used in current UK guidance.

Main Results:

Overall live birth rate was 22%, with the 30-34 age group showing the highest rate (28%).
Average rFSH dose was 1855 IU/cycle, with an average total cost of £2932/cycle.
Study costs per cycle were lower than those assumed in UK guidelines, despite comparable outcomes.

Conclusions:

Routine IVF/ICSI practice in this ACU achieved UK average outcomes at a lower total cost per cycle.
Lower rFSH dosages and associated protocols may allow for increased cycle provision within budgets.
Findings suggest that optimizing protocols can enhance the economic efficiency of assisted conception services.