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[Brugada syndrome--a brand new case]
Ruzica Jurcević1, Lazar Angelkov, Dejan Vukajlović
1Institut za kardiovaskularne bolesti Dedinje, Odeljenje za elektrofiziologiju i elektrostimulaciju, Beograd, Srbija. ruzicajurcevic@hotmail.com
Vojnosanitetski Pregled
|September 29, 2009
Summary
Brugada syndrome, a heart condition causing dangerous arrhythmias, was diagnosed in a Serbian woman using drug-induced electrocardiogram changes. An implantable defibrillator and medication successfully prevented further events.
Area of Science:
- Cardiology
- Electrophysiology
- Genetics
Background:
- Brugada syndrome (BS) is an inherited cardiac disorder.
- It is characterized by specific ECG abnormalities and risk of sudden cardiac death.
- Patients are prone to ventricular tachyarrhythmias.
Observation:
- A 58-year-old woman presented with palpitations and dizziness, not syncope.
- Her sister had died suddenly.
- ECG showed intermittent Type I pattern; Propafenone unmasked the syndrome.
- Electrophysiology study induced non-sustained ventricular tachycardia.
Findings:
- The patient had a history of palpitations and dizziness.
- Drug challenge unmasked Type I Brugada pattern.
- Electrophysiological study confirmed inducibility of ventricular tachycardia.
- Implantation of a cardioverter-defibrillator and medical therapy were initiated.
Implications:
- Early diagnosis and risk stratification are crucial for Brugada syndrome.
- Implantable cardioverter-defibrillators are indicated for high-risk patients.
- This case highlights the importance of electrophysiological studies in BS management.
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