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Related Concept Videos

Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a program...
Physiology of Enteric Nervous System and Gut Health01:05

Physiology of Enteric Nervous System and Gut Health

The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
Nerve Supply of the GI Tract01:27

Nerve Supply of the GI Tract

The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of the GI tract...
Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
What is a Nervous System?01:25

What is a Nervous System?

Overview
Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...

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Related Experiment Video

Updated: Jun 20, 2026

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
10:34

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse

Published on: August 7, 2013

Enteric nervous system development: Recent progress and future challenges.

Cátia Laranjeira1, Vassilis Pachnis

  • 1MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom. claranj@nimr.mrc.ac.uk

Autonomic Neuroscience : Basic & Clinical
|September 29, 2009
PubMed
Summary
This summary is machine-generated.

Recent research advances our understanding of the mammalian enteric nervous system's development. This review highlights key progress and future research directions for this critical component of the digestive system.

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Related Experiment Videos

Last Updated: Jun 20, 2026

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
10:34

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse

Published on: August 7, 2013

Immunostaining to Visualize Murine Enteric Nervous System Development
07:54

Immunostaining to Visualize Murine Enteric Nervous System Development

Published on: April 29, 2015

A Quantitative Cell Migration Assay for Murine Enteric Neural Progenitors
08:26

A Quantitative Cell Migration Assay for Murine Enteric Neural Progenitors

Published on: September 18, 2013

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Gastroenterology

Background:

  • The enteric nervous system (ENS), the largest part of the peripheral nervous system, is crucial for digestion.
  • Significant advancements have been made in understanding ENS development over the past 15 years.

Purpose of the Study:

  • To review recent progress in mammalian enteric nervous system development.
  • To identify key areas for future research in ENS development.

Main Methods:

  • Literature review of recent studies on ENS development.
  • Synthesis of current knowledge on molecular and cellular mechanisms.

Main Results:

  • Detailed overview of recent findings in mammalian ENS development.
  • Identification of remaining unanswered questions and knowledge gaps.

Conclusions:

  • Continued research is vital for a comprehensive understanding of ENS development.
  • Future studies should focus on the highlighted areas to address current limitations.