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Guidelines for management of atopic dermatitis
Hidehisa Saeki1, Masutaka Furue, Fukumi Furukawa
1Department of Dermatology, Graduate School of Medicine, University of Tokyo, Tokyo.
The Journal of Dermatology
|September 30, 2009
Summary
Atopic dermatitis (AD) management guidelines emphasize dermatological training for accurate diagnosis and severity assessment. Standard therapies include topical corticosteroids, emollients, and systemic treatments for inflammation and pruritus.
Area of Science:
- Dermatology
- Clinical Guideline Development
Background:
- Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin condition.
- AD presents with pruritus, inflammation, and impaired skin barrier function.
- Most AD patients exhibit atopic diathesis.
Purpose of the Study:
- To present a standard guideline for the management of atopic dermatitis.
- To emphasize the importance of dermatological training for AD diagnosis and severity assessment.
- To outline current therapeutic strategies for AD.
Main Methods:
- Definitive AD diagnosis requires pruritus, typical morphology/distribution, and a chronic relapsing course.
- Severity classification involves evaluating eruption elements and body region areas (max 60 points).
- Guideline incorporates standard therapies, including topical corticosteroids, tacrolimus ointment, emollients, and adjunctive treatments.
Main Results:
- A structured approach to AD diagnosis and severity classification is established.
- Standard therapies include topical corticosteroids and tacrolimus for inflammation, emollients for skin barrier, and systemic agents for pruritus.
- Specific tacrolimus ointment concentrations are indicated for different age groups.
Conclusions:
- The guideline underscores the necessity of dermatological expertise for effective AD management.
- Current therapies address inflammation, skin barrier dysfunction, and pruritus.
- Oral cyclosporine is noted as an option for severe, recalcitrant adult AD.
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