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An Acute Retinal Model for Evaluating Blood Retinal Barrier Breach and Potential Drugs for Treatment
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A system for computerised retinal haemorrhage analysis.

Tariq Aslam1, Paul Chua, Matthew Richardson

  • 1Moorfields Eye Hospital, London, UK. TAslam@AOL.COM

BMC Research Notes
|September 30, 2009
PubMed
Summary
This summary is machine-generated.

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Researchers developed an interactive system for measuring retinal hemorrhages in digital images. This tool, the Haemorrhage Assessment System (HAS), provides objective quantification for vitreoretinal hemorrhage research.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Computational Science

Background:

  • Developing automated systems for retinal hemorrhage measurement has been challenging.
  • User interaction proved necessary for achieving valid segmentation in hemorrhage assessment.
  • An interactive system was developed to address these limitations.

Purpose of the Study:

  • To create an objective, computerised system for measuring various retinal hemorrhages in digital images.
  • To provide a reliable research tool for quantitative analysis of vitreoretinal hemorrhages.

Main Methods:

  • Developed the Haemorrhage Assessment System (HAS), an interactive program with a graphical user interface.
  • Ophthalmologically trained users delineate hemorrhage types, optic disc, and fovea.

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  • The system automatically calculates quantitative measures like area, center of mass, and orientation.

    • Main Results:

    • The HAS allows users to delineate retinal features and automatically calculates various quantitative measures.
    • Evidence for HAS validity was established through comparisons with established software and geometric image results.
    • The system accurately quantifies features relevant to vitreoretinal hemorrhage studies.

    Conclusions:

    • The Haemorrhage Assessment System (HAS) is a valuable tool for researchers studying vitreoretinal hemorrhages.
    • It offers accurate quantification of an ophthalmologist's assessment of digital retinal images.
    • The system aids in studying the distribution and topography of retinal hemorrhages.