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Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
Published on: November 4, 2021
[Myocardial infarction aborted by rapid percutaneous coronary intervention]
Jeroen van Etten1, Freek W A Verheugt
1Onze Lieve Vrouwe Gasthuis, afd. Cardiologie, Amsterdam, The Netherlands.
Insights
Percutaneous coronary intervention with stenting may abort ST segment elevation myocardial infarction. This case series suggests PCI can normalize ECGs and limit cardiac enzyme release, offering promising results for acute myocardial infarction treatment.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Coronary Syndromes
Background:
- ST segment elevation myocardial infarction (STEMI) is a critical condition requiring rapid reperfusion.
- Fibrinolysis is an established treatment for aborting myocardial infarction.
- The efficacy of percutaneous coronary intervention (PCI) in aborting myocardial infarction remains less proven.
Observation:
- Two patients (55-year-old woman, 51-year-old man) presented with STEMI confirmed by electrocardiogram (ECG).
- Both patients underwent successful percutaneous coronary intervention with stenting.
- Rapid reperfusion therapy was administered to both individuals.
Findings:
- The ECG abnormalities normalized in both patients post-PCI.
- No significant cardiac enzyme abnormalities were detected in the blood after treatment.
- These outcomes suggest a potential for PCI to abort myocardial infarction.
Implications:
- PCI with stenting may be an effective strategy for aborting acute myocardial infarction.
- These findings warrant further investigation in larger clinical trials.
- Successful reperfusion via PCI could improve patient outcomes in STEMI.
Abstract:
In a 55-year-old woman and a 51-year-old man with an ST segment elevation myocardial infarction confirmed by ECG, the infarction could still be aborted by percutaneous coronary intervention with stenting. An aborted myocardial infarction can be described as an acute myocardial infarction in which rapid reperfusion therapy allows normalization of ECG abnormalities with no meaningful cardiac enzyme abnormalities found in the blood. Scientific evidence shows fibrinolysis to be effective in aborting myocardial infarction, but for percutaneous coronary intervention this has not been proven. Nevertheless, the results of the 2 cases discussed in our article are promising.
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