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Related Concept Videos

Microtubules in Cell Motility01:24

Microtubules in Cell Motility

Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
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Cell Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Actin Polymerization and Cell Motility01:13

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Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.
Cytoskeletal Coordination in Cell Migration01:32

Cytoskeletal Coordination in Cell Migration

A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker proteins that...

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Related Experiment Video

Updated: Jun 19, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Information mobility in complex networks.

Ernesto Estrada1

  • 1Department of Physics, Department of Mathematics, and Institute of Complex Systems, University of Strathclyde, Glasgow G1 1XH, United Kingdom. ernesto.estrada@strath.ac.uk

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|October 2, 2009
PubMed
Summary
This summary is machine-generated.

This study introduces information mobility in complex networks using fractional time stochastic processes. Scale-free networks show better information spread, but some real-world networks outperform them due to specific structural parameters.

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Area of Science:

  • Network Science
  • Statistical Physics
  • Information Theory

Background:

  • Complex networks are crucial for information dissemination.
  • Understanding information flow dynamics is essential for network analysis.
  • Existing models often lack a nuanced view of information mobility over time.

Purpose of the Study:

  • To introduce and define information mobility in complex networks.
  • To develop a framework using fractional calculus for analyzing information spread.
  • To compare information spreading efficiency in scale-free versus non-scale-free networks and real-world examples.

Main Methods:

  • Modeling information spread as a stochastic process on a network.
  • Utilizing fractional powers of the network's transition matrix.
  • Introducing a mobility coefficient based on the trace of fractional matrix powers.
  • Defining a metric for 50% information diffusion time (1/k(50)).

Main Results:

  • Scale-free random networks demonstrate superior information spreading capabilities compared to non-scale-free networks.
  • Analysis of 38 real-world networks reveals that some exhibit even better information diffusion than scale-free networks with similar average degrees.
  • Identification of key structural parameters contributing to enhanced information spread in real-world networks.

Conclusions:

  • Fractional calculus provides a powerful tool for quantifying information mobility in complex networks.
  • Network topology significantly impacts information diffusion efficiency.
  • Real-world network structures can possess unique properties that optimize information spread beyond idealized scale-free models.