Wolf-Parkinson-White alternans diagnosis unveiled by adenosine stress test

Rami N Khouzam1

  • 1Division of Cardiovascular Diseases, Farmington Heart Center, Farmington, NM, USA. khouzamrami@yahoo.com

Insights

Wolf-Parkinson-White syndrome can mimic heart attack on ECGs. This case highlights how intermittent preexcitation can be detected during stress testing, confirming the diagnosis.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Atypical chest pain presentation necessitates thorough diagnostic evaluation.
  • Electrocardiogram (ECG) interpretation is critical for diagnosing cardiac conditions.

Observation:

  • A patient initially diagnosed with left bundle-branch block and old infarct on ECG.
  • Subsequent normal ECG by a cardiologist prompted further investigation.
  • Transient preexcited beats observed during an adenosine nuclear stress test.

Findings:

  • Diagnosis of Wolf-Parkinson-White (WPW) syndrome confirmed by intermittent preexcitation during stress testing.
  • WPW syndrome can present with ECG findings mimicking other cardiac abnormalities, such as pseudoinfarct patterns.
  • Preexcitation alternans observed during adenosine stress test.

Implications:

  • Highlights the importance of considering WPW syndrome in atypical chest pain presentations with misleading ECGs.
  • Adenosine nuclear stress testing can be valuable in diagnosing conditions with intermittent ECG abnormalities.
  • Accurate diagnosis of WPW syndrome is crucial to prevent misdiagnosis and ensure appropriate management.

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