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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

[Neurologic emergency in children's hospital. Stroke]

A Palmieri1, A C Molinari, A Rossi

  • 1Unità Operativa di Medicina d'Urgenza, Centro Regionale di Trombosi ed Emostasi, Istituto Giannina Gaslini IRCCS, Genova, Italia. antonellapalmieri@ospedale-gaslini.ge.it

Minerva Pediatrica
|October 2, 2009
PubMed

Insights

Pediatric stroke diagnosis and treatment can be delayed. This study highlights the need for emergency room physician awareness of increasing childhood stroke cases and emphasizes a multidisciplinary approach for better outcomes.

Area of Science:

  • Pediatric Neurology
  • Emergency Medicine

Background:

  • Childhood stroke (pediatric stroke) incidence may be underestimated in emergency department (ED) settings.
  • Delayed diagnosis and treatment are significant concerns in pediatric stroke cases.

Purpose of the Study:

  • To raise awareness among emergency room physicians about the increasing incidence of stroke in children.
  • To analyze the presentation and treatment strategies for pediatric stroke cases admitted to a pediatric emergency department.

Main Methods:

  • A departmental study was conducted at Giannina Gasslini Children's Hospital, Genoa, Italy.
  • Retrospective analysis of 23 children admitted with stroke to the pediatric emergency department between 2001 and 2005.
  • Incidence rates were calculated for neurology and all pediatric patients.

Main Results:

  • The incidence of stroke among neurology patients was 0.8% and 0.02% among all pediatric patients (2001-2005).
  • This incidence may be lower than reported due to the exclusion of patients presenting at the ED at stroke onset.
  • Treatment strategies included anticoagulant or antiplatelet therapy, with homogeneous approaches for specific conditions like sickle cell disease, venous stroke, or heart disease.

Conclusions:

  • Pediatric stroke cases present diverse clinical manifestations and require varied therapeutic strategies.
  • Current treatment is often individualized, but a critical review indicates the necessity for a standardized multidisciplinary protocol.
Abstract

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