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Published on: July 27, 2022
Synthesis and structure of mono-bridged resorcinarene host: a ditopic receptor for ammonium guests
Kirsi Salorinne1, Tiia-Riikka Tero, Kaisa Riikonen
1Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box 35, 40014 JYU, Finland.
Abstract:
The synthesis and structural properties of tetramethoxy resorcinarene mono-crown-5 (1) are described. The binding characteristics of 1 toward acetylcholine and tetramethylammonium salts were investigated by 1H NMR titration. It was observed that the cavity of 1 provides a better fit to acetylcholine compared to the smaller tetramethylammonium cation, as acetylcholine is able to interact with both the crown ether moiety and the free hydroxyl groups of receptor 1 simultaneously.
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