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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

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Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

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Related Experiment Video

Updated: Jun 19, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Psoriasis comorbidities.

Lyn Guenther1, Wayne Gulliver

  • 1The Guenther Dermatology Research Centre, London, ON. dgue@gdrc.ca

Journal of Cutaneous Medicine and Surgery
|October 6, 2009
PubMed
Summary
This summary is machine-generated.

Patients with psoriasis often have serious comorbidities that reduce lifespan. Early screening and treatment of these conditions, including with biologic therapy, can improve outcomes and longevity.

Related Experiment Videos

Last Updated: Jun 19, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Immunology
  • Public Health

Background:

  • Psoriasis is linked to numerous systemic and behavioral comorbidities, many sharing similar immune pathways.
  • Studies indicate patients with psoriasis experience a significantly reduced lifespan due to these associated conditions.
  • Comorbidities can influence treatment choices for psoriasis and may preclude traditional systemic therapies.

Purpose of the Study:

  • To highlight the association between psoriasis and its comorbidities.
  • To emphasize the need for screening and managing these comorbidities in psoriasis patients.
  • To discuss the impact of comorbidities on psoriasis treatment and the role of biologic therapy.

Main Methods:

  • Literature review of studies on psoriasis comorbidities.
  • Analysis of the impact of comorbidities on patient lifespan and treatment options.
  • Evaluation of current treatment strategies, including biologic therapies, for patients with comorbidities.

Main Results:

  • Psoriatic arthritis, cardiovascular disease, diabetes, and mental health issues are common comorbidities.
  • Patients with psoriasis have a demonstrably shorter life expectancy compared to the general population.
  • Biologic therapies offer a safe and effective treatment option for psoriasis patients with pre-existing comorbidities.

Conclusions:

  • Dermatologists and primary care physicians should screen psoriasis patients for comorbidities.
  • Managing comorbidities is crucial for improving the quality of life and longevity of psoriasis patients.
  • Effective psoriasis management, potentially through biologics, may reduce mortality and prolong life.