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Updated: Jun 19, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Central venous lines and how to manage them
Ilaria Stolfi1, Francesca Boccanera, Castellano Chiara
1Neonatal Intensive Care Unit, Department of Pediatrics, Umberto I Policlinico of Rome, Sapienza University of Rome, Italy. ilaria.stolfi@gmail.com
Peripherally Inserted Central Venous Catheters (PICCs) are crucial for premature infants requiring long-term IV therapy. Proper insertion and management are essential to minimize complications and improve outcomes for neonates.
Area of Science:
- Neonatal clinical practice
- Vascular access
- Pediatric medicine
Background:
- Increasing survival rates of premature infants necessitate advanced neonatal care.
- Long-term intravenous (IV) fluid and medication administration is common in neonates.
- Central venous lines, specifically Peripherally Inserted Central Venous Catheters (PICCs), are preferred over peripheral lines for neonates.
Purpose of the Study:
- To outline key strategies for successful Peripherally Inserted Central Venous Catheter (PICC) insertion in neonates.
- To provide recommendations for optimal management of PICCs in neonatal patients.
- To address the impact of PICC complications on neonatal morbidity and mortality.
Main Methods:
- Review of current clinical practices and guidelines for PICC insertion.
- Analysis of literature on PICC-related complications in neonates.
- Synthesis of expert recommendations for PICC management.
Main Results:
- PICC insertion requires specific techniques to ensure success in neonates.
- Effective management strategies can mitigate risks associated with PICCs.
- Complications from PICCs can significantly impact neonatal health outcomes.
Conclusions:
- Successful PICC insertion and management are vital for neonatal care.
- Adherence to best practices minimizes PICC-related complications.
- Improved PICC protocols enhance the safety and efficacy of neonatal IV therapy.
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