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Updated: Jun 19, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Central venous lines and how to manage them
Ilaria Stolfi1, Francesca Boccanera, Castellano Chiara
1Neonatal Intensive Care Unit, Department of Pediatrics, Umberto I Policlinico of Rome, Sapienza University of Rome, Italy. ilaria.stolfi@gmail.com
Abstract:
The importance of vascular access in neonatal clinical practice is increasing, because of the survival of a larger number of premature babies, who require administration of long-term intravenous fluids and medications than in the past. In these newborn central venous lines are preferred to peripheral lines, particularly Peripherally Inserted Central Venous Catheter (PICC). Despite of the benefits of this device, PICC complications can negatively affect morbidity and mortality of the neonate. This article describes the principal strategies and recommendations for the success of the PICC insertion procedure and for its better management.
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