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Updated: Aug 15, 2026

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
Published on: May 21, 2015
[Effects of chorionic gonadotropin (hCG) therapy on the immune system]
M Maghnie1, A Valtorta, A Moretta
1Clinica Pediatrica, IRCCS Policlinico S. Matteo, Università di Pavia.
Abstract:
Humoral and cellular immunologic parameters were evaluated in 13 prepuberal cryptorchid boys before, during and 3 months after hCG therapy. Before treatment, all the immunologic parameters were normal except for a higher percentage of T suppressor-cytotoxic cells (CD8+). During therapy, the percentage of CD8+ cells and lymphocyte response to ConA significantly decreased, and returned to the control level after hCG withdrawal. The possible effects of long-term hCG treatment on the immune system remains to be determined.
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