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Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
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Related Experiment Video

Updated: Jun 19, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Clinical considerations regarding contralateral prophylactic mastectomy.

David R McCready1, Jaime Escallon

  • 1Gattuso Chair in Breast Surgical Oncology.

Women'S Health (London, England)
|October 7, 2009
PubMed
Summary
This summary is machine-generated.

Prophylactic mastectomy significantly reduces contralateral breast cancer risk by 95%. While complications exist, it

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Last Updated: Jun 19, 2026

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Published on: August 19, 2025

Area of Science:

  • Oncology
  • Surgical Oncology
  • Breast Cancer Research

Background:

  • Contralateral breast cancer (CBC) poses a significant risk following initial diagnosis.
  • Understanding risk factors and clinical features is crucial for prevention strategies.

Purpose of the Study:

  • To review risk factors and clinical features associated with contralateral breast cancer.
  • To evaluate the efficacy and patient satisfaction of prophylactic mastectomy for CBC prevention.

Main Methods:

  • Review of existing literature on contralateral breast cancer.
  • Analysis of data regarding adjuvant systemic treatments and prophylactic mastectomy outcomes.

Main Results:

  • Adjuvant systemic treatments offer some prevention, but prophylactic mastectomy provides the largest risk reduction (95%).
  • Patient satisfaction with prophylactic mastectomy is high in selected cases, though potential complications require careful consideration.

Conclusions:

  • Prophylactic mastectomy is a reasonable option for high-risk individuals with a good prognosis primary tumor.
  • Discussion of risks, benefits, and potential complications is essential before performing contralateral mastectomy, with or without reconstruction.