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Adenotonsillectomy and neurocognitive deficits in children with Sleep Disordered Breathing
Mark J Kohler1, Kurt Lushington, Cameron J van den Heuvel
1Children's Research Centre, University of Adelaide, North Adelaide, Australia. mark.kohler@adelaide.edu.au
Insights
Adenotonsillectomy resolves childhood sleep disordered breathing (SDB) but does not improve associated neurocognitive deficits. Further research is needed to address cognitive impairments in children with SDB.
Area of Science:
- Pediatric Sleep Medicine
- Neuroscience
- Otolaryngology
Background:
- Sleep Disordered Breathing (SDB) is a prevalent childhood condition characterized by upper airway obstruction during sleep.
- Children with SDB often exhibit significant neurocognitive deficits.
- Adenotonsillectomy is the primary treatment for SDB, but its impact on neurocognitive outcomes requires further investigation.
Purpose of the Study:
- To evaluate the effect of adenotonsillectomy on neurocognitive deficits in children with SDB.
- To compare neurocognitive outcomes in children with SDB post-surgery to non-snoring controls.
Main Methods:
- A cohort of 44 children (3-12 years) with SDB awaiting adenotonsillectomy and 48 age-matched controls underwent polysomnography and neurocognitive assessments.
- Assessments were conducted at baseline and 6-month follow-up post-surgery for the SDB group.
Main Results:
- SDB children presented with significant baseline neurocognitive deficits, including a 10-point IQ gap and impairments in language and executive function compared to controls.
- Adenotonsillectomy effectively improved respiratory parameters and reduced snoring frequency.
- No significant improvement in neurocognitive performance was observed in the SDB group relative to controls at 6-month follow-up.
Conclusions:
- Adenotonsillectomy is effective in treating the respiratory aspects of childhood SDB.
- Neurocognitive deficits associated with SDB in children did not show improvement 6 months after adenotonsillectomy.
Background:
Sleep Disordered Breathing (SDB) is a common childhood disorder that encompasses a range of sleep-related upper airway obstruction. Children with SDB demonstrate significant neurocognitive deficits. Adenotonsillectomy is the first line of treatment for SDB and whilst this improves respiratory disturbance, it remains to be established whether neurocognitive gains also result.
Methods:
A total of 44 healthy snoring children aged 3-12 years awaiting adenotonsillectomy (SDB group), and 48 age and gender matched non-snoring controls from the general community, completed the study. All children underwent polysomnography and neurocognitive assessment at baseline and after a 6-month follow-up (after surgery in the snoring group). Our primary aim was to determine whether neurocognitive deficits in snoring children were significantly improved following adenotonsillectomy.
Results:
Wide ranging neurocognitive deficits were found at baseline in SDB children compared to controls, most notably a 10 point IQ difference (P<.001) and similar deficits in language and executive function. Whilst adenotonsillectomy improved respiratory parameters and snoring frequency at 6 months post surgery, neurocognitive performance did not improve relative to controls.
Conclusion:
Adenotonsillectomy successfully treated the respiratory effects of SDB in children. However, neurocognitive deficits did not improve 6-months post-operatively.
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