Reactive oxygen species enhance insulin sensitivity

Kim Loh1, Haiyang Deng, Atsushi Fukushima

  • 1Department of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia.

Cell Metabolism
|October 8, 2009
PubMed
Summary

Mice lacking glutathione peroxidase 1 (Gpx1) showed improved insulin sensitivity and were protected from diet-induced insulin resistance. This suggests reactive oxygen species (ROS) enhance insulin signaling in vivo.

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