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Related Concept Videos

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...

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Related Experiment Video

Updated: Jun 19, 2026

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
06:34

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants

Published on: January 21, 2020

PMRD: plant microRNA database.

Zhenhai Zhang1, Jingyin Yu, Daofeng Li

  • 1State Key Laboratory of Plant Physiology and Biochemistry and State Key Laboratory for Agricultural Biotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China.

Nucleic Acids Research
|October 8, 2009
PubMed
Summary
This summary is machine-generated.

The Plant MicroRNA Database (PMRD) integrates plant microRNA (miRNA) data, offering sequences, targets, and expression profiles for 121 species. This resource aids researchers in studying miRNA functions in plants.

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mirMachine: A One-Stop Shop for Plant miRNA Annotation
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mirMachine: A One-Stop Shop for Plant miRNA Annotation

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RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs
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RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs

Published on: July 11, 2020

Related Experiment Videos

Last Updated: Jun 19, 2026

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
06:34

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants

Published on: January 21, 2020

mirMachine: A One-Stop Shop for Plant miRNA Annotation
06:16

mirMachine: A One-Stop Shop for Plant miRNA Annotation

Published on: May 1, 2021

RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs
14:41

RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs

Published on: July 11, 2020

Area of Science:

  • Plant Biology
  • Bioinformatics
  • Genomics

Background:

  • MicroRNAs (miRNAs) are crucial non-coding small RNAs regulating gene expression in eukaryotes.
  • They play vital roles in plant growth and development, with increasing research interest.
  • Availability of plant genome sequences necessitates integrated data resources.

Purpose of the Study:

  • To develop a comprehensive plant miRNA database (PMRD) by integrating public and in-house data.
  • To provide a centralized resource for plant miRNA sequences, structures, targets, and expression profiles.
  • To facilitate research on miRNA function and target genes in model plants and crops.

Main Methods:

  • Integrated publicly available plant miRNA data from databases and literature.
  • Incorporated in-house generated miRNA data.
  • Developed a user-friendly web interface with search tools and a genome browser.

Main Results:

  • PMRD contains 8433 miRNAs from 121 plant species, including major crops and model plants.
  • Includes predicted target genes for miRNAs in key species like Arabidopsis, rice, and soybean.
  • Provides miRNA expression profiles from microarray data for various plant species.

Conclusions:

  • PMRD serves as a valuable, freely accessible tool for plant miRNA research.
  • Facilitates the study of miRNA functions and target gene interactions.
  • Supports research in both model plants and agriculturally important crops.