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Updated: Jun 19, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
Blood pressure and pulse wave velocity values in the institutionalized elderly aged 80 and over: baseline of the
Athanase Benetos1, Severine Buatois, Paolo Salvi
1Department of Geriatrics, University Hospital of Nancy, Nancy, France. a.benetos@chu-nancy.fr
Insights
This study found that elderly nursing home residents have distinct hemodynamic profiles, with increased pulse pressure and aortic stiffness correlating with age. These findings highlight the need for further research into blood pressure and arterial stiffness in this population.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Public Health
Background:
- The PARTAGE study investigates hemodynamic characteristics in very elderly institutionalized individuals.
- Understanding blood pressure and arterial stiffness is crucial for predicting health outcomes in this demographic.
Purpose of the Study:
- To determine the predictive value of blood pressure and arterial stiffness for mortality, cardiovascular events, and cognitive decline.
- To present baseline data from a large population of institutionalized patients aged 80 and over.
Main Methods:
- Recruited 1130 nursing home residents (878 women) from French and Italian facilities.
- Collected clinical and 3-day self-measured blood pressure data.
- Measured aortic and upper limb pulse wave velocity using a PulsePen tonometer.
Main Results:
- High prevalence of hypertension (76% women, 60% men), with over 91% on antihypertensive treatment.
- 51% of treated hypertensive patients achieved well-controlled systolic blood pressure (<140 mmHg).
- Age-related increases in pulse pressure due to decreased diastolic BP; aortic pulse wave velocity increased significantly with age.
Conclusions:
- Institutionalized elderly exhibit different hemodynamic profiles compared to community-dwelling elders.
- Arterial stiffness, particularly aortic, shows age-related changes in this population.
- Longitudinal assessment of blood pressure and arterial stiffness is warranted to understand morbidity and mortality risks.
Objective:
The aim of the longitudinal study PARTAGE (predictive values of blood pressure and arterial stiffness in institutionalized very aged population) was to determine the predictive value of blood pressure (BP) and arterial stiffness for overall mortality, major cardiovascular events and cognitive decline in a large population of institutionalized patients aged 80 and over. In the study herein, we present the baseline data values of this study.
Methods:
A total of 1130 patients were recruited (878 women), living in French and Italian nursing homes. Clinical and 3-day self-measurements of BP were conducted. Aortic and upper limb pulse wave velocity were obtained using a PulsePen tonometer.
Results:
Of this population, 76% of women and 60% of men had a known hypertension and over 91% of the patients were under antihypertensive treatment; 51% of the treated hypertensive patients were well controlled (systolic BP <140 mmHg). No significant differences were found between clinical and self-measured BP. With age, there was an increase in pulse pressure (P < 0.001) due to a decrease in diastolic BP (P < 0.001), without any increase in systolic BP. Aortic but not peripheral pulse wave velocity significantly increased with age (P < 0.005).
Conclusion:
Baseline values obtained herein demonstrate that elderly patients living in nursing homes present hemodynamic characteristics which are different to those described in community-living elderly populations, and indicate the interest of assessing, in longitudinal studies, the role of BP and arterial stiffness in morbidity and mortality in this population.
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