Related Experiment Video
Updated: Jun 19, 2026

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
Published on: September 26, 2019
Acute effects of formalin on pulmonary functions in gross anatomy laboratory
Farah Khaliq1, Praveen Tripathi
1Department of Physiology, University College of Medical Sciences & G.T.B. Hospital, Dilshad Garden, Shahadara, Delhi 110 095. farahphysio@yahoo.com
Abstract:
Formaldehyde is a common indoor pollutant with irritant properties. The present study was undertaken in first year medical students to study the acute effects of it on their first exposure in gross anatomy laboratory. Twenty randomly selected subjects aged between 18 to 20 years and non smokers had undergone pulmonary function testing thrice. First being baseline values then immediately after their first dissection class (2 hrs.) and lastly 24 hrs after their first exposure. All the tests were performed on Siblemed 120 B portable spirometer with inbuilt computer programme under standard laboratory conditions. It was observed that FVC decreased in subjects immediately after their first exposure but reverted back to normal within 24 hrs. While all other lung function parameters remained unchanged, indicating some mild transient bronchoconstriction on acute exposure to formalin. The study needs to be extended with larger number of subjects.
More Related Videos
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
14:48Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
Published on: March 21, 2021
Related Concept Videos
Atelectasis II: Pathophysiology
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...