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Updated: Jun 19, 2026

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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
Published on: October 25, 2015
[Foetal reduction--a retrospective survey].
Mette Heinel Frederiksen1, Stine Dam Henriksen, Astrid Julie Bønnelykke
1Gynaekologisk-Obstetrisk Afdeling Y, Arhus Universitetshospital, Skejby, DK-8200 Arhus N. mettef@yahoo.com
Ugeskrift for Laeger
|October 9, 2009
Summary
Selective foetal reduction in multiple pregnancies, performed via intracardial potassium chloride injection, shows outcomes comparable to international standards. Reducing to a singleton pregnancy improves gestational length, birth weight, and reduces growth restriction compared to reducing to twins.
Area of Science:
- Maternal-Fetal Medicine
- Reproductive Medicine
- Perinatology
Context:
- Selective foetal reduction is a procedure to manage multi-foetal pregnancies.
- Outcomes of this procedure in Denmark were previously unstudied.
- Aarhus University Hospital, Skejby, initiated a study to evaluate their foetal reduction outcomes.
Purpose:
- To retrospectively analyze the outcomes of selective foetal reduction procedures.
- To compare outcomes of reducing multiple pregnancies to twins versus singletons.
- To establish a Danish benchmark for foetal reduction success rates.
Summary:
- A retrospective analysis of 70 foetal reductions was conducted.
- Reducing 44 multiple pregnancies to twins resulted in a 5% foetal loss rate and improved perinatal outcomes.
- Reducing to a singleton pregnancy demonstrated superior results in gestational age, birth weight, and reduced growth restriction.
Impact:
- The study provides crucial data on selective foetal reduction in a Danish cohort.
- Findings suggest that reducing to a singleton pregnancy is associated with better neonatal outcomes.
- Results align with international standards, informing clinical practice and patient counseling.

