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Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

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Updated: Jun 19, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

An update on exercise-induced bronchoconstriction with and without asthma.

Chris Randolph¹

¹Center for Allergy, Asthma, and Immunology, Yale University Affiliated Programs, 1389 West Main Street, Suite 205, Waterbury, CT 06708, USA. ccrandmd@aol.com

Current Allergy and Asthma Reports

|October 10, 2009

Summary

Exercise-induced bronchoconstriction (EIB) is a reversible airway narrowing triggered by exercise. This review covers its diverse presentations, diagnosis, and management in athletes and military personnel.

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Last Updated: Jun 19, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

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A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

Area of Science:

Sports Medicine
Pulmonology
Exercise Physiology

Background:

Exercise-induced bronchoconstriction (EIB) is a common condition in athletes.
It presents as a spectrum of phenotypes, from asymptomatic cases detected via challenge tests to elite athletes experiencing it as an overuse injury.
EIB can occur independently or in conjunction with underlying asthma.

Purpose of the Study:

To provide a comprehensive overview of exercise-induced bronchoconstriction (EIB).
To discuss the pathogenesis, clinical presentation, diagnostic approaches, and management strategies for EIB and EIB with asthma.

Main Methods:

This is a review article.
It synthesizes current knowledge on EIB and EIB with asthma.

Main Results:

EIB is characterized by transient, reversible bronchoconstriction post-exercise.
Distinguishing between EIB alone and EIB associated with asthma is crucial for appropriate management.
Management strategies should be tailored to the individual's phenotype and clinical presentation.

Conclusions:

EIB is a complex syndrome with varied presentations in athletes and other populations.
Accurate diagnosis and tailored management are essential for optimizing performance and well-being.
Further research into the specific pathogenetic mechanisms of different EIB phenotypes may yield more targeted therapies.