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Updated: Jun 19, 2026

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
Published on: May 18, 2022
Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and
Jan Gruber1, Li Fang Ng, Suresh Kumar Poovathingal
1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Abstract:
The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model organism for aging studies as well as for testing antioxidants and other compounds for effects on longevity. However, results in the literature are sometimes confusing and contradictory. This review introduces C. elegans as a model organism, discusses aspects that make it attractive for aging and antioxidant research, and addresses some problems and potential artifacts.
