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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
Published on: March 24, 2017
Cutaneous vasculitis associated with interferon beta-1b treatment for multiple sclerosis
Jarmila Szilasiová1, Zuzana Gdovinová, Jagienka Jautová
1Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia. jarmila.szilasiova@upjs.sk
Abstract:
We report a 38-year-old woman with relapsing-remitting multiple sclerosis, treated with subcutaneous injections of interferon beta (IFN-beta)-1b every other day. Disseminated cutaneous lesions were observed after 3 injections. These symptoms reappeared after drug readministration. The histopathological examination of the skin specimens confirmed nonspecific cutaneous lymphocytic vasculitis. The patient's outcome was favorable after corticosteroid placement and discontinuing IFN-beta therapy. Isolated lymphocytic cutaneous vasculitis linked to IFN-beta-1b therapy is suspected as a new association.
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