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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Bilayers coating on titanium surface: the impact on the hydroxyapatite initiation.
Christelle Arnould1, Jessica Denayer, Michael Planckaert
1Laboratory of Chemistry and Electrochemistry of Surfaces, University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium.
Journal of Colloid and Interface Science
|October 14, 2009
Summary
This study developed a new tantalum oxide and organophosphonic acid bilayer coating for orthopaedic devices. This surface modification enhances corrosion resistance and promotes hydroxyapatite growth, improving implant longevity.
Area of Science:
- Biomaterials Science
- Surface Engineering
- Orthopaedic Implants
Background:
- Orthopaedic devices made of titanium alloys suffer from ion release and loosening.
- Surface modification is essential to overcome these limitations.
- Previous work focused on inorganic/organic bilayer coatings.
Purpose of the Study:
- To develop and improve a multifunctional inorganic/organic bilayer coating.
- To investigate the effect of this coating on corrosion resistance.
- To evaluate the hydroxyapatite growth rate and osteoinduction properties.
Main Methods:
- Sol-gel synthesis of a tantalum oxide layer.
- Modification of the tantalum oxide layer with organophosphonic acids.
- Immersion in simulated body fluid to assess corrosion and hydroxyapatite growth.
Main Results:
- The bilayer coating demonstrated improved corrosion resistance.
- Enhanced hydroxyapatite growth rate was observed.
- The structure of the organophosphonic acid significantly influenced osteoinduction.
Conclusions:
- The developed bilayer coating offers a promising solution for orthopaedic device limitations.
- Surface chemistry, specifically organophosphonic acid structure, is critical for osteoinduction.
- This approach enhances implant biocompatibility and long-term stability.
