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Updated: Jun 19, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Intravenous fluid therapy - an under-recognized patient safety opportunity
1Bishop Auckland General Hospital, Co Durham, UK. stuart.smellie@cddft.nhs.uk
Fluid overload is a significant, underestimated cause of patient harm, morbidity, and mortality. Standardized fluid management guidelines, like GIFTASUP, can improve patient care and reduce adverse events.
Area of Science:
- Critical Care Medicine
- Nephrology
- Hospital Administration
Background:
- Inappropriate fluid administration is a potential cause of patient harm.
- Fluid overload is an under-recognized contributor to patient morbidity and mortality.
- Existing evidence suggests a need for improved fluid management protocols.
Purpose of the Study:
- To highlight the under-documented risks of inappropriate fluid regimens.
- To advocate for standardized fluid management practices in hospitals.
- To explore the potential of guidelines like GIFTASUP in improving patient outcomes.
Main Methods:
- Review of existing literature and evidence on fluid management.
- Analysis of the implications of fluid overload on patient health.
- Consideration of the GIFTASUP guidelines (2008) for fluid management standardization.
Main Results:
- Inappropriate fluid regimens are rarely documented as a direct cause of harm.
- Circumstantial evidence strongly suggests fluid overload is a significant factor in patient morbidity and mortality.
- The GIFTASUP guidelines present an opportunity for standardized fluid management.
Conclusions:
- Fluid overload is a critical, under-appreciated factor in patient outcomes.
- Standardized fluid management, potentially supported by hospital services, is necessary.
- Adoption of guidelines like GIFTASUP can promote better clinical practice and patient safety.
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