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Updated: Jun 19, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Adult outcomes of preterm children
1Division of Neonatology, Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA. mxh7@case.edu
Insights
Most preterm infants who survive neonatal intensive care live normal adult lives, with outcomes influenced by gestational age and family socioeconomic status.
Area of Science:
- Neonatology
- Developmental Pediatrics
- Adult Health Outcomes
Background:
- Neonatal intensive care has improved survival rates for preterm infants.
- Long-term adult outcomes for these survivors are increasingly studied.
Purpose of the Study:
- To evaluate the adult outcomes of individuals who received neonatal intensive care as preterm infants.
- To identify predictors of adult outcomes in this population.
Main Methods:
- Review of adult outcomes including neurodevelopmental, behavioral, health, social functioning, and reproduction.
- Comparison of preterm survivors to control groups.
Main Results:
- Preterm survivors showed statistically significant differences in most outcomes compared to controls.
- The majority of preterm survivors achieve good adult outcomes and live normal lives.
- Lower gestational age and family sociodemographic status were key predictors of adult outcomes.
Conclusions:
- While differences exist, most preterm survivors adapt well into adulthood.
- Perinatal injury (indicated by gestational age) and socioeconomic factors significantly impact long-term health and development.
Abstract:
The survivors of the initial years of neonatal intensive care of preterm infants reached adulthood during the last decade. Reports of their adult outcomes examined have included neurodevelopmental, behavioral and health outcomes as well as social functioning and reproduction. Despite statistically significant differences between preterm young adults and controls in most outcomes studied, the majority of preterm survivors do well and live fairly normal lives. The two major predictors of adult outcomes are lower gestational age that reflect perinatal injury and family sociodemographic status which reflects both genetic and environmental effects.
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