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Updated: Jun 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Beware of the pet dog: a case of Staphylococcus intermedius infection
Russell Kempker1, Deepa Mangalat, Thiphasone Kongphet-Tran
1Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA. rkempke@emory.edu
Abstract:
Staphylococcus intermedius is a common commensal and pathogen in dogs and cats and only rarely has been identified as causing human infection. We report a human case of postoperative sinus infection caused by methicillin-resistant S. intermedius. A 28-year-old woman with a history of endoscopic pituitary adenoma resection presented with 3 weeks of foul smelling nasal discharge. Nasal endoscopy revealed purulent sinus drainage. Cultures, initially misidentified as coagulase-negative Staphylococcus and then as Staphylococcus aureus, revealed the presence of S. intermedius. Cultures from the patient's pet dog also grew S. intermedius strains that were confirmed to be identical to those of the patient's by pulse field gel electrophoresis analysis. The patient was successfully treated with endoscopic debridement and a prolonged antibiotic regimen with vancomycin and linezolid. Our case illustrates the possibility of transmission of antibiotic-resistant bacteria causing infection from pets to humans.
Insights
Methicillin-resistant Staphylococcus intermedius, a common pet bacteria, can cause human sinus infections. This case highlights potential pet-to-human transmission of antibiotic-resistant bacteria.
Area of Science:
- Veterinary Medicine
- Infectious Diseases
- Human Health
Background:
- Staphylococcus intermedius is a common bacteria in dogs and cats.
- Human infections are rare, but this case involved a methicillin-resistant strain.
Purpose of the Study:
- To report a rare human sinus infection caused by Staphylococcus intermedius.
- To investigate the source of infection and potential transmission from pets.
Main Methods:
- Case report of a human sinus infection.
- Bacterial culturing and identification, including initial misidentification.
- Pulse field gel electrophoresis (PFGE) for bacterial strain comparison.
- Nasal endoscopy and surgical debridement.
Main Results:
- A methicillin-resistant Staphylococcus intermedius sinus infection was diagnosed in a patient post-surgery.
- Identical S. intermedius strains were isolated from the patient and her pet dog.
- The patient's infection was successfully treated with antibiotics and surgery.
Conclusions:
- Staphylococcus intermedius can cause serious human infections, particularly in immunocompromised individuals.
- Pet-to-human transmission of antibiotic-resistant bacteria is a significant concern.
- Accurate and timely bacterial identification is crucial for effective treatment.
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