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Updated: Jun 19, 2026
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Analysis of Histone Antibody Specificity with Peptide Microarrays
Published on: August 1, 2017
Hydrolytic activity of histidine-containing octapeptides in water identified by quantitative screening of a
Carsten Schmuck1, Ute Michels, Jürgen Dudaczek
1Institute of Organic Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45141 Essen, Germany. carsten.schmuck@uni-due.de
Organic & Biomolecular Chemistry
|October 16, 2009
Abstract:
A quantitative on-bead screening of a combinatorial octapeptide library revealed catalysts with hydrolytic activity in water. Histidine is an essential amino acid but the catalytic activity as well as the substrate binding affinity is also dependent on the sequence of the octapeptide.
