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Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries

Tammy L Romanuik1, Gang Wang, Robert A Holt

  • 1Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. tromanuik@cw.bc.ca

BMC Genomics
|October 17, 2009
PubMed
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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...