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Dandy-Walker malformation: analysis of 19 cases.

George A Alexiou1, George Sfakianos, Neofytos Prodromou

  • 1Department of Neurosurgery, Children's Hospital Agia Sofia, Athens, Greece. alexiougrg@yahoo.gr

Journal of Child Neurology
|October 17, 2009
PubMed
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Surgical treatment for Dandy-Walker malformation, a congenital brain disorder, showed positive outcomes in 19 cases. Various surgical approaches, including cyst and ventricular drainage, led to patient improvement.

Area of Science:

  • Neuroscience
  • Pediatric Neurology
  • Congenital Disorders

Background:

  • Dandy-Walker malformation is a congenital neurological disorder affecting the cerebellum and fourth ventricle.
  • Optimal surgical management for Dandy-Walker malformation remains a subject of debate.
  • Associated brain and extracranial abnormalities are common in Dandy-Walker malformation.

Purpose of the Study:

  • To evaluate the surgical outcomes of Dandy-Walker malformation patients treated at our institute.
  • To assess the effectiveness of different surgical strategies for Dandy-Walker malformation with hydrocephalus.

Main Methods:

  • Retrospective analysis of 19 consecutive Dandy-Walker malformation cases diagnosed between 1992 and 2008.
  • Surgical interventions included combined ventricular and posterior fossa cyst drainage, posterior fossa cyst drainage alone, or ventricular drainage alone.

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  • All patients presented with hydrocephalus and underwent surgical treatment.

    • Main Results:

    • All 19 patients with Dandy-Walker malformation showed improvement following surgical treatment.
    • Surgical approaches varied: 5 with combined drainage, 10 with cyst drainage, and 4 with ventricular drainage.
    • The study highlights the varied prognosis dependent on syndrome severity and comorbidities.

    Conclusions:

    • Surgical intervention for Dandy-Walker malformation, particularly when associated with hydrocephalus, can lead to positive patient outcomes.
    • Different surgical techniques may be employed based on individual patient presentation.
    • Further research is needed to establish the optimum surgical management for Dandy-Walker malformation.