[Obstetrical and pediatric impact of in utero cocaine exposure]

C Lejeune1, A-M Simonpoli, P Gressens

  • 1Service de Néonatologie, Hôpital Louis Mourier, Colombes, France. claude.lejeune@lmr.aphp.fr

Review of recent publications about perinatal consequences of cocaine use during pregnancy points out that: - dramatic obstetrical, neonatal and developmental abnormalities, reported during 1980-90', are less frequent in recent cohort studies; - pregnant women who use cocaine or crack, also consume other psychoactive drugs (alcohol, tobacco, benzodiazepines, cannabis, opiates, ...) and have a very chaotic life-style; so, it is difficult to distinguish abnormalities caused by cocaine per se, even with numerous cohorts, control groups and multivariate analysis.