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Updated: Jun 19, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
07:54

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials

Published on: October 27, 2020

Engineered nanoparticle surfaces for improved mass spectrometric analyses.

Zheng-Jiang Zhu1, Vincent M Rotello, Richard W Vachet

  • 1Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.

The Analyst
|October 20, 2009
PubMed
Summary
This summary is machine-generated.

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See all related articles

Surface-engineered nanoparticles offer controlled biomolecule interactions and enhance mass spectrometry. This review explores integrating these nanoparticles for improved analysis of chemical and biological systems.

Area of Science:

  • Nanotechnology
  • Analytical Chemistry
  • Biochemistry

Background:

  • Nanoparticle surface functionality is crucial for controlled interactions with biomolecules like lipids, proteins, and nucleic acids.
  • Surface chemistry engineering of nanoparticles opens new possibilities for enhancing analytical techniques.

Purpose of the Study:

  • To review emerging research integrating surface-engineered nanoparticles with mass spectrometry.
  • To highlight advancements in analyzing chemical and biological systems using this integrated approach.

Main Methods:

  • Focuses on the integration of surface-engineered nanoparticles with mass spectrometry.
  • Discusses the control of nanoparticle surface chemistry for specific interactions.

Main Results:

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In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
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In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

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Last Updated: Jun 19, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
07:54

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials

Published on: October 27, 2020

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
10:22

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

  • Surface engineering of nanoparticles enables precise control over biomolecule interactions.
  • Integration with mass spectrometry significantly improves the analysis of diverse chemical and biological samples.

Conclusions:

  • Surface-engineered nanoparticles combined with mass spectrometry represent a powerful tool for advanced chemical and biological analysis.
  • This synergistic approach offers new avenues for high-resolution characterization of complex systems.