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Published on: April 22, 2019
Oral squamous cell carcinoma: a clinicopathological study of 342 Thai cases
Aree Jainkittivong1, Somporn Swasdison, Malee Thangpisityotin
1Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. Aree.J@chula.ac.th
Aim:
To conduct a clinicopathological review of oral squamous cell carcinoma (SCC) and to analyze it with respect to gender, age at diagnosis, clinical presentation, lesion location, and histological grading.
Methods And Materials:
Information on the clinicopathological characteristics of SCC was obtained from pathology reports of 342 cases.
Results:
The male to female ratio was 1:1 and the incidence increased with age. Among the patients 4.7% were younger than 40 years and males were predominant in this subgroup. The alveolar ridge and gingiva were the most commonly affected sites (50%). The majority of the SCC cases presented as ulcers or masses. Swelling and/or pain were the first signs and/or symptoms in most patients (52.6%). The age at diagnosis in relation to the site of occurrence varied. Conventional SCC was the most common subtype (88%). Well-differentiated SCC was the most common histological grading (78.6%).
Conclusion:
In the present study, the incidence of SCC was age-related and showed equal gender distribution.
Clinical Significance:
Routine examination of the oral cavity by dental practitioners and other health care providers aids in the early detection of premalignant and malignant oral disease. Dentists can play a significant role in disseminating information regarding oral cancer.
