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Published on: May 24, 2016
In-transit metastasis from melanoma presenting as lymphangiectasis: a case report
Tatyana Shekhel1, Ronald M Glick, Lee D Cranmer
1Midwestern University, Glendale, Arizona, USA. tshekhel@hotmail.com
Cutis
|October 22, 2009
Summary
In-transit metastasis (ITM) is a rare skin manifestation of malignant melanoma. Early detection and high suspicion are crucial for managing melanoma patients with unusual skin lesions.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Malignant melanoma can rarely present as inflammatory skin metastasis.
- In-transit metastasis (ITM) describes melanoma spread between the primary tumor and regional lymph nodes.
Observation:
- A patient with a history of high-risk left lower extremity melanoma developed unusual left leg lesions.
- These lesions clinically resembled lymphangiectasis, a condition affecting lymphatic vessels.
Findings:
- Punch biopsy confirmed atypical cells consistent with melanoma.
- The clinical presentation was an unusual manifestation of in-transit metastasis.
Implications:
- This case underscores the importance of a high index of suspicion for ITM in melanoma patients.
- Recognizing rare presentations of melanoma metastasis is vital for timely diagnosis and treatment planning.
