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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

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Updated: Jun 19, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Osteoarticular tuberculosis in Tehran, Iran: a 2-year study.

A Hadadi1, M Rasoulinejad, P Khashayar

  • 1Research Development Centre, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. hadadiaz@tums.ac.ir

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|October 23, 2009
PubMed
Summary
This summary is machine-generated.

Osteoarticular tuberculosis (TB) is challenging to diagnose due to non-specific symptoms. This study highlights common sites and complications of osteoarticular TB in Iran, emphasizing its importance in high-prevalence regions.

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Last Updated: Jun 19, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Area of Science:

  • Infectious Diseases
  • Orthopedics
  • Public Health

Background:

  • Osteoarticular tuberculosis (TB) comprises 1-5% of all TB cases and 10-18% of extrapulmonary TB.
  • Diagnosis is often delayed due to the absence of specific clinical signs and symptoms, as pulmonary involvement is rare.

Purpose of the Study:

  • To determine the frequency of osteoarticular TB.
  • To analyze the clinical and laboratory findings associated with osteoarticular TB.
  • To identify common sites and complications of osteoarticular TB in Tehran, Iran.

Main Methods:

  • Retrospective review of hospital data for patients diagnosed with osteoarticular TB between 2003 and 2005.
  • Analysis of demographic data, clinical presentations, and radiological and pathological findings.

Main Results:

  • Common constitutional symptoms included weight loss (50%), fever (36%), and night sweats (38.5%).
  • Most frequent sites for TB arthritis were the knee, ankle, hip, and shoulder.
  • TB spondylitis most commonly affected the lumbar (22.7%) and thoracic (50%) vertebrae. Complications included sphincter disorder (39.1%) and paraplegia (28.9%).

Conclusions:

  • Osteoarticular TB presents with varied constitutional symptoms and affects multiple joint and bone sites.
  • High prevalence of complications like sphincter disorder and paraplegia underscores the severity of the condition.
  • Osteomyelitis due to TB should be considered in TB-prevalent areas.