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Identification of the HLA-Cw*0774 and DQB1*060105 alleles

R O Endres1, H Redman, N Marcus

  • 1HLA Laboratory, Blood Systems Laboratories, Tempe, AZ 85282, USA. rendres@bloodsystems.org

Tissue Antigens
|October 23, 2009
PubMed

Abstract:

Cw*0774 differs from Cw*070201 by one nucleotide within the coding sequence of exons 2-4. DQB1*060105 differs from DQB1*060101 by one nucleotide within the coding sequence of exons 2-3.

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
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