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Remote Laboratory Management: Respiratory Virus Diagnostics
Published on: April 6, 2019
Progress toward poliomyelitis eradication--Nigeria, January 2008-July 2009
Abstract:
Although wild poliovirus (WPV) cases in Nigeria decreased from 1,129 in 2006 to 285 in 2007, Nigeria had the world's highest polio burden in 2008, with 798 (48%) of 1,651 WPV cases reported globally, including 721 (74%) of 976 WPV type 1 (WPV1) cases. This report provides an update on progress toward polio eradication in Nigeria during 2008-2009 and activities planned to interrupt transmission. During 2008-2009, Nigeria was the source for WPV1 transmission to 11 countries and WPV type 3 (WPV3) transmission to four countries. In addition, transmission of circulating type 2 vaccine-derived poliovirus (cVDPV2) has been ongoing since 2005. WPV1 cases decreased 87%, from 574 during January-July 2008 to 73 for the same period in 2009. However, WPV3 cases rose approximately six-fold, from 51 during January-July 2008 to 303 during the same period in 2009, partly because of the increased emphasis on controlling WPV1. The decline in the proportion of children who have never received oral poliovirus vaccine (OPV) in the highest- incidence northern states, from 31% in 2006 to 11% in the first half of 2009 indicates progress toward eradication. During 2008-2009, activities to accelerate polio eradication included use of mobile teams to vaccinate children not at home during supplemental immunization activities (SIAs), and efforts to increase political oversight and the engagement of community leaders. Sustained support of traditional, religious, and political leaders and improved implementation of SIAs will be needed to interrupt WPV and cVDPV2 transmission.
Insights
Nigeria faced a high polio burden in 2008 despite case declines. Efforts in 2008-2009 focused on interrupting wild poliovirus (WPV) and circulating vaccine-derived poliovirus type 2 (cVDPV2) transmission.
Area of Science:
- Public Health
- Epidemiology
- Virology
Background:
- Nigeria remained a global hotspot for wild poliovirus (WPV) in 2008, despite previous reductions.
- The country was a significant source of WPV type 1 (WPV1) and WPV type 3 (WPV3) transmission internationally.
- Ongoing transmission of circulating type 2 vaccine-derived poliovirus (cVDPV2) presented a persistent challenge.
Purpose of the Study:
- To provide an update on polio eradication progress in Nigeria during 2008-2009.
- To outline planned activities to interrupt poliovirus transmission.
- To assess the impact of interventions on vaccination coverage.
Main Methods:
- Analysis of WPV and cVDPV2 case data from 2008-2009.
- Monitoring of WPV1 and WPV3 transmission dynamics.
- Evaluation of vaccination coverage, particularly in high-incidence northern states.
Main Results:
- WPV1 cases significantly decreased by 87% between January-July 2008 and 2009.
- WPV3 cases increased approximately six-fold during the same period.
- The proportion of unvaccinated children in northern states dropped from 31% in 2006 to 11% in early 2009, indicating progress.
Conclusions:
- Interrupting WPV and cVDPV2 transmission requires sustained engagement of leaders and improved supplemental immunization activities (SIAs).
- Targeted strategies, including mobile vaccination teams, are crucial for reaching unvaccinated children.
- Continued political and community support is essential for achieving polio eradication in Nigeria.
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