Related Experiment Video
Updated: Jun 19, 2026
03:49
Application of Microwave Ablation in Laparoscopic Partial Splenectomy
Published on: November 15, 2024
Palliative spleen irradiation: can we standardize its technique?
Mohamed Soliman Nazmy1, Aida Radwan, Maha Mokhtar
1The Department of Radiotherapy, National Cancer Institute, Cairo University, Cairo, Egypt. mnazmy@hotmail.com
Journal of the Egyptian National Cancer Institute
|October 23, 2009
Summary
Palliative splenic irradiation (PSI) offers significant symptom relief for CML and CLL patients. The single anterior field technique is effective and safe, though higher doses may benefit CLL patients.
Area of Science:
- Oncology
- Radiation Oncology
- Palliative Care
Background:
- Splenic irradiation is used for symptomatic relief in hematologic malignancies.
- Patterns of practice for palliative splenic irradiation (PSI) can vary.
Purpose of the Study:
- To explore the practice patterns of palliative splenic irradiation (PSI) at the National Cancer Institute, Cairo University.
- To compare common planning techniques for PSI.
Main Methods:
- Retrospective review of medical records for patients receiving PSI between 1990 and 2005.
- Comparison of three planning techniques: parallel opposing, single direct field, and anterior/lateral fields.
Main Results:
- Eighteen patients (13 CML, 5 CLL) received PSI, with spleen enlargement in all.
- The single direct anterior field was most common; all patients reported subjective improvement.
- Significant increases in hemoglobin and decreases in WBC count were observed.
Conclusions:
- Palliative splenic irradiation provides significant palliative benefit.
- Single anterior field is a suitable technique, alongside parallel opposing fields.
- Higher doses may be required for chronic lymphocytic leukemia (CLL) compared to chronic myeloid leukemia (CML).
