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Updated: Jun 19, 2026
07:25
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Palliative systemic therapy of castration-resistant prostate cancer: current developments]
1Urologische Universitätsklinik, Ulm, Deutschland. florian.finter@uniklinik-ulm.de
Der Urologe. Ausg. A
|October 23, 2009
Summary
Advanced prostate cancer treatment options after docetaxel therapy are limited. This review explores emerging therapies including targeted treatments and immunomodulation for advanced prostate cancer. Future prostate cancer management may involve these novel approaches.
Area of Science:
- Oncology
- Urology
- Medical Research
Background:
- Androgen withdrawal and docetaxel chemotherapy are standard for advanced prostate cancer.
- Limited evidence exists for therapies following docetaxel progression.
- New treatment strategies are crucial for advanced prostate cancer management.
Purpose of the Study:
- To provide an overview of investigational therapies for advanced prostate cancer post-docetaxel treatment.
- To highlight emerging treatment modalities beyond current standards of care.
- To inform clinicians about future therapeutic options for refractory prostate cancer.
Main Methods:
- Literature review of clinical trials and scientific publications.
- Analysis of data on targeted therapy, immunotherapy, and other novel agents.
- Synthesis of information on investigational approaches for advanced prostate cancer.
Main Results:
- Several novel therapeutic classes are under investigation.
- These include endothelin inhibitors, immunotherapies, and multikinase inhibitors.
- Radionuclide approaches also show promise in clinical trials.
Conclusions:
- Emerging therapies offer potential new avenues for advanced prostate cancer.
- Targeted therapy and immunomodulation are key areas of focus.
- Further research is needed to establish the efficacy of these agents in clinical practice.
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