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Updated: Jun 19, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
[Bioproduction of pharmaceutical proteins: review and perspectives]
Joëlle Dumas1, Bénédicte Robert
1Genopole Campus 1, Evry, France. joelle.dumas@genopole.fr
Abstract:
The increase in importance of the biopharmaceutical market generates enormous needs in production of therapeutic molecules. The world capacities of production, mainly therapeutic proteins, impossible to obtain by chemical synthesis, are at present insufficient. Besides the economic aspects in set, play, the question of the technologies used to produce these molecules is important: the tried(felt) technologies (bacteria, yeasts, cells of mammals), used for a long time rather widely remain expensive, or see their limited field of application; the innovative technologies (avian cells, animal and plant transgenic, among others), as for them, again have to show their ability.
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