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Identification and quantitation of trace impurities in fatty alcohol ethoxylates using HPLC and MALDI-TOF mass

Dean Lee1, Steve Rumbelow, S Kim Ratanathanawongs Williams

  • 1Laboratory for Advanced Separations Technologies, Department of Chemistry and Geochemistry, Colorado School of Mines, Golden, CO 80401, USA.

Analytica Chimica Acta
|October 24, 2009
PubMed

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MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...