Related Experiment Video
Updated: Jun 19, 2026

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
Primary and secondary immune response to measles vaccine strain
W Abramow-Newerly1, B Litwińska, J Litwińska
1Department of Virology, National Institute of Hygiene, Chocimska 24, 00-791 Warszawa, Poland.
Abstract:
The rates of primary and secondary cell-mediated immune responses and their correlation with humoral responses were estimated. Cell-mediated reactions were evaluated by the leucocyte migration inhibition test. No significant differences were found in the intensity of primary and secondary cellular responses. The cell-mediated response was not intensified by complete Freund adjuvant, which stimulated the humoral response. The kinetics of changes in cell-mediated reaction was comparable with that observed for other viruses.
Related Concept Videos
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Vaccinations
Vaccines
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Cross-reactivity

