Practical considerations for prostate HDR brachytherapy
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Updated: Jun 19, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
1Department of Radiation Oncology, IU Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA. edslessi@iupui.edu
Purpose:
A process for prostate high-dose-rate (HDR) brachytherapy was developed and implemented successfully in the community hospital setting. The practical aspects of the program are reviewed and may serve as a foundation for clinics interested in offering this clinical service.
Methods And Materials:
A generic needle distribution geometry was established to accommodate target volumes of variable size. A system to identify and assign treatment channels to each implant needle was devised. The computerized tomography (CT)-based treatment planning was used with dose constraints defined for sensitive structures and target uniformity. Implant needle stability was promoted by supporting the patient on a CT compatible padded sliding board. A process that aligns dwell position to CT imaging without the use of radiographic markers was followed. Graphical optimization of dwell times was used to generate the treatment dose distributions.
Results:
Prostate HDR brachytherapy as a boost or as monotherapy has been offered in a program that has evolved over the past 8 years. Practical aspects of the program promote its feasibility and precision. Collaboration with commercial entities has also led to the development of products that support the technique.
Conclusions:
Prostate HDR brachytherapy offers a relatively high degree of dose distribution control in comparison with other prostate radiotherapy modalities. The practical aspects described offer assurance to achieve that goal.

