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Updated: Jun 19, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
[Head and neck squamous cell cancer]
Abstract:
Head and neck squamous cell carcinoma (HNSCC) is relatively common and is strongly related to smoking and alcohol consumption but infection by human papillomavirus has also emerged as a risk factor for HNSCC. The treatment of these tumors is complicated and patients are best served by a multidisciplinary team. The therapy now commonly involves a multidisciplinary approach including surgery, radiation treatment and chemotherapy. Lower stage disease carries a relatively good prognosis. The treatment of metastatic HNSCC remains unsatisfactory and the prognosis of these patients is poor.
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