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Updated: Jun 19, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Chronic inflammatory bowel diseases in children and adolescents]
Merja Ashorn1, Sari Iltanen, Kaija-Leena Kolho
1TAYS:n lastenklinikka, PL 2000, 33521 Tampere.
Insights
Inflammatory bowel disease (IBD) is rising in children and adolescents, presenting aggressively with unclear causes. Early diagnosis and tailored treatment are vital for growth, development, and quality of life.
Area of Science:
- Pediatric Gastroenterology
- Chronic Disease Epidemiology
- Immunology
Context:
- Increasing incidence of pediatric inflammatory bowel disease (IBD) in Western countries, including Finland.
- Etiology and triggers of IBD in young individuals remain largely unknown.
- Paediatric IBD often presents with a more aggressive clinical course compared to adult-onset disease.
Purpose:
- To highlight the challenges and therapeutic considerations in managing pediatric inflammatory bowel disease.
- To emphasize the importance of optimal medical management for supporting normal growth and pubertal development.
- To underscore the need for improved diagnostic tools and consideration of psychosocial impacts.
Summary:
- Pediatric IBD is characterized by aggressive clinical presentation and requires treatment strategies aligned with adult protocols.
- New serological and fecal analyses are improving diagnostic accuracy and disease screening in children.
- Effective management is critical for normal physical development and must address quality of life and psychosocial well-being.
Impact:
- Early and accurate diagnosis through advanced analyses can lead to timely intervention.
- Optimized treatment supports crucial developmental milestones in affected children and adolescents.
- Addressing the psychosocial health and quality of life is essential for comprehensive care in severe pediatric IBD cases.
Abstract:
Chronic inflammatory bowel diseases in children and adolescents Inflammatory bowel disease (IBD) is further increasing in children and adolescents in most Western countries including Finland. The etiologic factors of IBD and possible triggers have remained unclear. The clinical picture in paediatric IBD is more aggressive than in adults and operative intervention is common. Medical therapy is basically in line with the therapy used in adult patients. Optimal treatment is crucial in order to support normal growth and pubertal development. New serological and fecal analyses enhance the diagnostic accuracy and help the screening of the disease. The impact of IBD into the quality of life and psychosocial health has to be considered especially in severe cases.
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